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While graviola has shown promise against some forms of cancer in laboratory studies, it has also been shown to have possibly dangerous neurological side effects. Since few clinical studies have been run to determine the safety and efficacy of the supplement, it cannot be recommended. Graviola contains a chemical called annonaceous acetogenins, which is thought to be the active ingredient. Extracts of graviola have been shown to be effective against a number of viruses, bacteria and parasites in test tubes. Laboratory studies have also shown graviola to be effective against certain breast cancer cells that are resistant to the chemotherapy drug Adriamycin. It is thought that the extract is able to block the cancer cell's access to ATP, the source of energy for the cancer cell. Substances derived from graviola have also been found to damage nerve cells in test tubes as well. This may cause neurological effects similar to Parkinson's disease. Purported Uses: #1. To treat cancer - Graviola has been shown to be effective against cancer in a test tube, but no studies have been run to determine if it would have a similar effect in humans. #2. To treat herpes - Graviola has been shown to be effective against the herpes virus in a test tube, but no studies have been run to determine if it would have a similar effect in humans. #3. To fight infections - Graviola has been shown to be effective against some bacteria in a test tube, but no studies have been run to determine if it would have a similar effect in humans. #4. To fight parasitic infections - Graviola has been shown to be effective against some parasites in a test tube, but no studies have been run to determine if it would have a similar effect in humans. #5. As a sedative - No studies have evaluated graviola as a sedative. Warnings: This product is regulated by the FDA as a dietary supplement. Unlike approved drugs, supplements are not required to be manufactured under specific standardized conditions.